Preparation of co-crystals of human PPARα-LBD and ligand for high-resolution X-ray crystallography

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptor-type transcription factors with three subtypes (α, δ, and γ) that regulate cell differentiation and metabolism. Co-crystals of human PPARα-ligand-binding domain (LBD)-PPARα ligand for X-ray crystallography have been difficult t...

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Detalles Bibliográficos
Autores principales: Kamata, Shotaro, Oyama, Takuji, Ishii, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933539/
https://www.ncbi.nlm.nih.gov/pubmed/33718889
http://dx.doi.org/10.1016/j.xpro.2021.100364

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