Interleukin-6 Knockout Inhibits Senescence of Bone Mesenchymal Stem Cells in High-Fat Diet-Induced Bone Loss

Obesity, a chronic low-grade inflammatory state, not only promotes bone loss, but also accelerates cell senescence. However, little is known about the mechanisms that link obesity, bone loss, and cell senescence. Interleukin-6 (IL-6), a pivotal inflammatory mediator increased during obesity, is a ca...

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Detalles Bibliográficos
Autores principales: Li, Yujue, Lu, Lingyun, Xie, Ying, Chen, Xiang, Tian, Li, Liang, Yan, Li, Huifang, Zhang, Jie, Liu, Yi, Yu, Xijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933660/
https://www.ncbi.nlm.nih.gov/pubmed/33679606
http://dx.doi.org/10.3389/fendo.2020.622950

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