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STAT3 Silencing and TLR7/8 Pathway Activation Repolarize and Suppress Myeloid-Derived Suppressor Cells From Breast Cancer Patients

Cancer cells escape immune destruction. From this perspective, myeloid-derived suppressor cells (MDSCs), which are immunosuppressive in various cancers including breast cancer (BC), are significant. However, the precise mechanisms are unknown. We isolated HLA-DR(-)CD33(+) MDSCs and CD3(+) T cells fr...

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Detalles Bibliográficos
Autores principales:	Safarzadeh, Elham, Mohammadi, Ali, Mansoori, Behzad, Duijf, Pascal H. G., Hashemzadeh, Shahryar, Khaze, Vahid, Kazemi, Tohid, Derakhshani, Afshin, Silvestris, Nicola, Baradaran, Behzad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933669/ https://www.ncbi.nlm.nih.gov/pubmed/33679700 http://dx.doi.org/10.3389/fimmu.2020.613215

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