Whole-Exome Sequencing and hiPSC Cardiomyocyte Models Identify MYRIP, TRAPPC11, and SLC27A6 of Potential Importance to Left Ventricular Hypertrophy in an African Ancestry Population

Background: Indices of left ventricular (LV) structure and geometry represent useful intermediate phenotypes related to LV hypertrophy (LVH), a predictor of cardiovascular (CV) disease (CVD) outcomes. Methods and Results: We conducted an exome-wide association study of LV mass (LVM) adjusted to heig...

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Detalles Bibliográficos
Autores principales: Irvin, Marguerite R., Aggarwal, Praful, Claas, Steven A., de las Fuentes, Lisa, Do, Anh N., Gu, C. Charles, Matter, Andrea, Olson, Benjamin S., Patki, Amit, Schwander, Karen, Smith, Joshua D., Srinivasasainagendra, Vinodh, Tiwari, Hemant K., Turner, Amy J., Nickerson, Deborah A., Rao, Dabeeru C., Broeckel, Ulrich, Arnett, Donna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933688/
https://www.ncbi.nlm.nih.gov/pubmed/33679876
http://dx.doi.org/10.3389/fgene.2021.588452

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