Neurotrophic keratitis after penetrating keratoplasty for lattice dystrophy

PURPOSE: To report clinical outcomes of a patient with unilateral neurotrophic keratitis following penetrating keratoplasty for lattice dystrophy treated with topical recombinant human nerve growth factor. OBSERVATIONS: A 75-year-old male with lattice dystrophy and history of herpes simplex keratiti...

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Detalles Bibliográficos
Autores principales: Gouvea, Larissa, Penatti, Raphael, Rocha, Karolinne Maia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933712/
https://www.ncbi.nlm.nih.gov/pubmed/33718661
http://dx.doi.org/10.1016/j.ajoc.2021.101058
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author Gouvea, Larissa
Penatti, Raphael
Rocha, Karolinne Maia
author_facet Gouvea, Larissa
Penatti, Raphael
Rocha, Karolinne Maia
author_sort Gouvea, Larissa
collection PubMed
description PURPOSE: To report clinical outcomes of a patient with unilateral neurotrophic keratitis following penetrating keratoplasty for lattice dystrophy treated with topical recombinant human nerve growth factor. OBSERVATIONS: A 75-year-old male with lattice dystrophy and history of herpes simplex keratitis, presented with recurrent neurotrophic ulceration in the right eye two years following penetrating keratoplasty. The patient was successfully treated with topical recombinant human nerve growth factor. CONCLUSION: Neurotrophic keratitis is a rare chronic disorder that affects quality of life due to the risk of vision loss. Topical recombinant human nerve growth factor is a novel and effective treatment option that may help improve optical quality and patient's satisfaction as shown in this case of recurrent neurotrophic keratitis.
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spelling pubmed-79337122021-03-12 Neurotrophic keratitis after penetrating keratoplasty for lattice dystrophy Gouvea, Larissa Penatti, Raphael Rocha, Karolinne Maia Am J Ophthalmol Case Rep Case Report PURPOSE: To report clinical outcomes of a patient with unilateral neurotrophic keratitis following penetrating keratoplasty for lattice dystrophy treated with topical recombinant human nerve growth factor. OBSERVATIONS: A 75-year-old male with lattice dystrophy and history of herpes simplex keratitis, presented with recurrent neurotrophic ulceration in the right eye two years following penetrating keratoplasty. The patient was successfully treated with topical recombinant human nerve growth factor. CONCLUSION: Neurotrophic keratitis is a rare chronic disorder that affects quality of life due to the risk of vision loss. Topical recombinant human nerve growth factor is a novel and effective treatment option that may help improve optical quality and patient's satisfaction as shown in this case of recurrent neurotrophic keratitis. Elsevier 2021-02-26 /pmc/articles/PMC7933712/ /pubmed/33718661 http://dx.doi.org/10.1016/j.ajoc.2021.101058 Text en © 2021 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Gouvea, Larissa
Penatti, Raphael
Rocha, Karolinne Maia
Neurotrophic keratitis after penetrating keratoplasty for lattice dystrophy
title Neurotrophic keratitis after penetrating keratoplasty for lattice dystrophy
title_full Neurotrophic keratitis after penetrating keratoplasty for lattice dystrophy
title_fullStr Neurotrophic keratitis after penetrating keratoplasty for lattice dystrophy
title_full_unstemmed Neurotrophic keratitis after penetrating keratoplasty for lattice dystrophy
title_short Neurotrophic keratitis after penetrating keratoplasty for lattice dystrophy
title_sort neurotrophic keratitis after penetrating keratoplasty for lattice dystrophy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933712/
https://www.ncbi.nlm.nih.gov/pubmed/33718661
http://dx.doi.org/10.1016/j.ajoc.2021.101058
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