Role of the long non-coding RNA LINC00052 in tumors

Long intergenic non-protein coding RNA 52 (LINC00052) is a non-coding RNA with >200 nucleotides in length, which exerts important effects on several physiological and pathological processes of the human body. Recent studies have demonstrated that LINC00052 plays key roles in the tumorigenesis, pr...

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Detalles Bibliográficos
Autores principales: Xiong, Dongmei, Wang, Dan, Chen, Yanmeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933760/
https://www.ncbi.nlm.nih.gov/pubmed/33692848
http://dx.doi.org/10.3892/ol.2021.12577
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author Xiong, Dongmei
Wang, Dan
Chen, Yanmeng
author_facet Xiong, Dongmei
Wang, Dan
Chen, Yanmeng
author_sort Xiong, Dongmei
collection PubMed
description Long intergenic non-protein coding RNA 52 (LINC00052) is a non-coding RNA with >200 nucleotides in length, which exerts important effects on several physiological and pathological processes of the human body. Recent studies have demonstrated that LINC00052 plays key roles in the tumorigenesis, progression and metastasis of multiple types of human cancer, including hepatocellular carcinoma, breast cancer, colorectal cancer, cervical carcinoma and gastric cancer. However, the associations between LINC00052 and these tumors remain unclear. The present review summarizes the biological functions of LINC00052 during the pathogenic process of certain tumors, and discusses its potential therapeutic targets.
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spelling pubmed-79337602021-03-09 Role of the long non-coding RNA LINC00052 in tumors Xiong, Dongmei Wang, Dan Chen, Yanmeng Oncol Lett Review Long intergenic non-protein coding RNA 52 (LINC00052) is a non-coding RNA with >200 nucleotides in length, which exerts important effects on several physiological and pathological processes of the human body. Recent studies have demonstrated that LINC00052 plays key roles in the tumorigenesis, progression and metastasis of multiple types of human cancer, including hepatocellular carcinoma, breast cancer, colorectal cancer, cervical carcinoma and gastric cancer. However, the associations between LINC00052 and these tumors remain unclear. The present review summarizes the biological functions of LINC00052 during the pathogenic process of certain tumors, and discusses its potential therapeutic targets. D.A. Spandidos 2021-04 2021-02-23 /pmc/articles/PMC7933760/ /pubmed/33692848 http://dx.doi.org/10.3892/ol.2021.12577 Text en Copyright: © Xiong et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Review
Xiong, Dongmei
Wang, Dan
Chen, Yanmeng
Role of the long non-coding RNA LINC00052 in tumors
title Role of the long non-coding RNA LINC00052 in tumors
title_full Role of the long non-coding RNA LINC00052 in tumors
title_fullStr Role of the long non-coding RNA LINC00052 in tumors
title_full_unstemmed Role of the long non-coding RNA LINC00052 in tumors
title_short Role of the long non-coding RNA LINC00052 in tumors
title_sort role of the long non-coding rna linc00052 in tumors
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933760/
https://www.ncbi.nlm.nih.gov/pubmed/33692848
http://dx.doi.org/10.3892/ol.2021.12577
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