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Minimizing Population Health Loss in Times of Scarce Surgical Capacity During the Coronavirus Disease 2019 Crisis and Beyond: A Modeling Study

OBJECTIVES: Coronavirus disease 2019 has put unprecedented pressure on healthcare systems worldwide, leading to a reduction of the available healthcare capacity. Our objective was to develop a decision model to estimate the impact of postponing semielective surgical procedures on health, to support...

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Autores principales: Gravesteijn, Benjamin, Krijkamp, Eline, Busschbach, Jan, Geleijnse, Geert, Helmrich, Isabel Retel, Bruinsma, Sophie, van Lint, Céline, van Veen, Ernest, Steyerberg, Ewout, Verhoef, Kees, van Saase, Jan, Lingsma, Hester, Baatenburg de Jong, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: ISPOR-The Professional Society for Health Economics and Outcomes Research. Published by Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933792/
https://www.ncbi.nlm.nih.gov/pubmed/33933233
http://dx.doi.org/10.1016/j.jval.2020.12.010
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author Gravesteijn, Benjamin
Krijkamp, Eline
Busschbach, Jan
Geleijnse, Geert
Helmrich, Isabel Retel
Bruinsma, Sophie
van Lint, Céline
van Veen, Ernest
Steyerberg, Ewout
Verhoef, Kees
van Saase, Jan
Lingsma, Hester
Baatenburg de Jong, Rob
author_facet Gravesteijn, Benjamin
Krijkamp, Eline
Busschbach, Jan
Geleijnse, Geert
Helmrich, Isabel Retel
Bruinsma, Sophie
van Lint, Céline
van Veen, Ernest
Steyerberg, Ewout
Verhoef, Kees
van Saase, Jan
Lingsma, Hester
Baatenburg de Jong, Rob
author_sort Gravesteijn, Benjamin
collection PubMed
description OBJECTIVES: Coronavirus disease 2019 has put unprecedented pressure on healthcare systems worldwide, leading to a reduction of the available healthcare capacity. Our objective was to develop a decision model to estimate the impact of postponing semielective surgical procedures on health, to support prioritization of care from a utilitarian perspective. METHODS: A cohort state-transition model was developed and applied to 43 semielective nonpediatric surgical procedures commonly performed in academic hospitals. Scenarios of delaying surgery from 2 weeks were compared with delaying up to 1 year and no surgery at all. Model parameters were based on registries, scientific literature, and the World Health Organization Global Burden of Disease study. For each surgical procedure, the model estimated the average expected disability-adjusted life-years (DALYs) per month of delay. RESULTS: Given the best available evidence, the 2 surgical procedures associated with most DALYs owing to delay were bypass surgery for Fontaine III/IV peripheral arterial disease (0.23 DALY/month, 95% confidence interval [CI]: 0.13-0.36) and transaortic valve implantation (0.15 DALY/month, 95% CI: 0.09-0.24). The 2 surgical procedures with the least DALYs were placing a shunt for dialysis (0.01, 95% CI: 0.005-0.01) and thyroid carcinoma resection (0.01, 95% CI: 0.01-0.02). CONCLUSION: Expected health loss owing to surgical delay can be objectively calculated with our decision model based on best available evidence, which can guide prioritization of surgical procedures to minimize population health loss in times of scarcity. The model results should be placed in the context of different ethical perspectives and combined with capacity management tools to facilitate large-scale implementation.
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spelling pubmed-79337922021-03-05 Minimizing Population Health Loss in Times of Scarce Surgical Capacity During the Coronavirus Disease 2019 Crisis and Beyond: A Modeling Study Gravesteijn, Benjamin Krijkamp, Eline Busschbach, Jan Geleijnse, Geert Helmrich, Isabel Retel Bruinsma, Sophie van Lint, Céline van Veen, Ernest Steyerberg, Ewout Verhoef, Kees van Saase, Jan Lingsma, Hester Baatenburg de Jong, Rob Value Health Themed Section: COVID-19 OBJECTIVES: Coronavirus disease 2019 has put unprecedented pressure on healthcare systems worldwide, leading to a reduction of the available healthcare capacity. Our objective was to develop a decision model to estimate the impact of postponing semielective surgical procedures on health, to support prioritization of care from a utilitarian perspective. METHODS: A cohort state-transition model was developed and applied to 43 semielective nonpediatric surgical procedures commonly performed in academic hospitals. Scenarios of delaying surgery from 2 weeks were compared with delaying up to 1 year and no surgery at all. Model parameters were based on registries, scientific literature, and the World Health Organization Global Burden of Disease study. For each surgical procedure, the model estimated the average expected disability-adjusted life-years (DALYs) per month of delay. RESULTS: Given the best available evidence, the 2 surgical procedures associated with most DALYs owing to delay were bypass surgery for Fontaine III/IV peripheral arterial disease (0.23 DALY/month, 95% confidence interval [CI]: 0.13-0.36) and transaortic valve implantation (0.15 DALY/month, 95% CI: 0.09-0.24). The 2 surgical procedures with the least DALYs were placing a shunt for dialysis (0.01, 95% CI: 0.005-0.01) and thyroid carcinoma resection (0.01, 95% CI: 0.01-0.02). CONCLUSION: Expected health loss owing to surgical delay can be objectively calculated with our decision model based on best available evidence, which can guide prioritization of surgical procedures to minimize population health loss in times of scarcity. The model results should be placed in the context of different ethical perspectives and combined with capacity management tools to facilitate large-scale implementation. ISPOR-The Professional Society for Health Economics and Outcomes Research. Published by Elsevier Inc. 2021-05 2021-03-05 /pmc/articles/PMC7933792/ /pubmed/33933233 http://dx.doi.org/10.1016/j.jval.2020.12.010 Text en © 2021 ISPOR-The Professional Society for Health Economics and Outcomes Research. Published by Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Themed Section: COVID-19
Gravesteijn, Benjamin
Krijkamp, Eline
Busschbach, Jan
Geleijnse, Geert
Helmrich, Isabel Retel
Bruinsma, Sophie
van Lint, Céline
van Veen, Ernest
Steyerberg, Ewout
Verhoef, Kees
van Saase, Jan
Lingsma, Hester
Baatenburg de Jong, Rob
Minimizing Population Health Loss in Times of Scarce Surgical Capacity During the Coronavirus Disease 2019 Crisis and Beyond: A Modeling Study
title Minimizing Population Health Loss in Times of Scarce Surgical Capacity During the Coronavirus Disease 2019 Crisis and Beyond: A Modeling Study
title_full Minimizing Population Health Loss in Times of Scarce Surgical Capacity During the Coronavirus Disease 2019 Crisis and Beyond: A Modeling Study
title_fullStr Minimizing Population Health Loss in Times of Scarce Surgical Capacity During the Coronavirus Disease 2019 Crisis and Beyond: A Modeling Study
title_full_unstemmed Minimizing Population Health Loss in Times of Scarce Surgical Capacity During the Coronavirus Disease 2019 Crisis and Beyond: A Modeling Study
title_short Minimizing Population Health Loss in Times of Scarce Surgical Capacity During the Coronavirus Disease 2019 Crisis and Beyond: A Modeling Study
title_sort minimizing population health loss in times of scarce surgical capacity during the coronavirus disease 2019 crisis and beyond: a modeling study
topic Themed Section: COVID-19
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933792/
https://www.ncbi.nlm.nih.gov/pubmed/33933233
http://dx.doi.org/10.1016/j.jval.2020.12.010
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