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ORMDL3 Functions as a Negative Regulator of Antigen-Mediated Mast Cell Activation via an ATF6-UPR-Autophagy–Dependent Pathway

Antigen (Ag)-mediated mast cell activation plays a critical role in the immunopathology of IgE-dependent allergic diseases. Restraining the signaling cascade that regulates the release of mast cell-derived inflammatory mediators is an attractive therapeutic strategy to treat allergic diseases. Oroso...

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Detalles Bibliográficos
Autores principales:	Li, Jia, Ullah, Md Ashik, Jin, Hongping, Liang, Yuting, Lin, Lihui, Wang, Juan, Peng, Xia, Liao, Huanjin, Li, Yanning, Ge, Yiqin, Li, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933793/ https://www.ncbi.nlm.nih.gov/pubmed/33679742 http://dx.doi.org/10.3389/fimmu.2021.604974

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