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Membrane therapy using DHA suppresses epidermal growth factor receptor signaling by disrupting nanocluster formation

Epidermal growth factor receptor (EGFR) signaling drives the formation of many types of cancer, including colon cancer. Docosahexaenoic acid (DHA, 22∶6(Δ4,7,10,13,16,19)), a chemoprotective long-chain n-3 polyunsaturated fatty acid suppresses EGFR signaling. However, the mechanism underlying this ph...

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Detalles Bibliográficos
Autores principales:	Fuentes, Natividad R., Mlih, Mohamed, Wang, Xiaoli, Webster, Gabriella, Cortes-Acosta, Sergio, Salinas, Michael L., Corbin, Ian R., Karpac, Jason, Chapkin, Robert S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933808/ https://www.ncbi.nlm.nih.gov/pubmed/33515553 http://dx.doi.org/10.1016/j.jlr.2021.100026

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