Cargando…
In vitro differentiation of human embryonic stem cells to hemogenic endothelium and blood progenitors via embryoid body formation
Little is known about the emergence of blood progenitors during human embryogenesis due to ethical reasons and restricted embryo access. The use of human embryonic stem cells (hESCs) as a model system offers unique opportunities to dissect human blood cell formation. Here, we describe a protocol all...
Autores principales: | Garcia-Alegria, Eva, Potts, Bethany, Menegatti, Sara, Kouskoff, Valerie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933812/ https://www.ncbi.nlm.nih.gov/pubmed/33718891 http://dx.doi.org/10.1016/j.xpro.2021.100367 |
Ejemplares similares
-
Early Human Hemogenic Endothelium Generates Primitive and Definitive Hematopoiesis In Vitro
por: Garcia-Alegria, Eva, et al.
Publicado: (2018) -
The RUNX1b Isoform Defines Hemogenic Competency in Developing Human Endothelial Cells
por: Menegatti, Sara, et al.
Publicado: (2021) -
CD82 expression marks the endothelium to hematopoietic transition at the onset of blood specification in human
por: Menegatti, Sara, et al.
Publicado: (2023) -
HOXB4 Promotes Hemogenic Endothelium Formation without Perturbing Endothelial Cell Development
por: Teichweyde, Nadine, et al.
Publicado: (2018) -
Regulation of RUNX1 dosage is crucial for efficient blood formation from hemogenic endothelium
por: Lie-A-Ling, Michael, et al.
Publicado: (2018)