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Unexpected PD‐L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies

Lack of effective immune infiltration represents a significant barrier to immunotherapy in solid tumors. Thus, solid tumor‐enriched death receptor‐5 (DR5) activating antibodies, which generates tumor debulking by extrinsic apoptotic cytotoxicity, remains a crucial alternate therapeutic strategy. Ove...

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Detalles Bibliográficos
Autores principales:	Mondal, Tanmoy, Shivange, Gururaj N, Tihagam, Rachisan GT, Lyerly, Evan, Battista, Michael, Talwar, Divpriya, Mosavian, Roxanna, Urbanek, Karol, Rashid, Narmeen S, Harrell, J Chuck, Bos, Paula D, Stelow, Edward B, Stack, M Sharon, Bhatnagar, Sanchita, Tushir‐Singh, Jogender
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933954/ https://www.ncbi.nlm.nih.gov/pubmed/33587338 http://dx.doi.org/10.15252/emmm.202012716

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