COVID-19 vaccines: modes of immune activation and future challenges

The new vaccines against SARS-CoV-2 are novel in terms of specificity, their wide dissemination across the global population and the inclusion of newly licensed mRNA platforms. We discuss here how the approved vaccines trigger innate immunity to promote durable immunological memory and consider the...

Descripción completa

Detalles Bibliográficos
Autores principales: Teijaro, John R., Farber, Donna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934118/
https://www.ncbi.nlm.nih.gov/pubmed/33674759
http://dx.doi.org/10.1038/s41577-021-00526-x
_version_ 1783660760471175168
author Teijaro, John R.
Farber, Donna L.
author_facet Teijaro, John R.
Farber, Donna L.
author_sort Teijaro, John R.
collection PubMed
description The new vaccines against SARS-CoV-2 are novel in terms of specificity, their wide dissemination across the global population and the inclusion of newly licensed mRNA platforms. We discuss here how the approved vaccines trigger innate immunity to promote durable immunological memory and consider the future implications of protecting populations with these vaccines.
format Online
Article
Text
id pubmed-7934118
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-79341182021-03-05 COVID-19 vaccines: modes of immune activation and future challenges Teijaro, John R. Farber, Donna L. Nat Rev Immunol Comment The new vaccines against SARS-CoV-2 are novel in terms of specificity, their wide dissemination across the global population and the inclusion of newly licensed mRNA platforms. We discuss here how the approved vaccines trigger innate immunity to promote durable immunological memory and consider the future implications of protecting populations with these vaccines. Nature Publishing Group UK 2021-03-05 2021 /pmc/articles/PMC7934118/ /pubmed/33674759 http://dx.doi.org/10.1038/s41577-021-00526-x Text en © Springer Nature Limited 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Comment
Teijaro, John R.
Farber, Donna L.
COVID-19 vaccines: modes of immune activation and future challenges
title COVID-19 vaccines: modes of immune activation and future challenges
title_full COVID-19 vaccines: modes of immune activation and future challenges
title_fullStr COVID-19 vaccines: modes of immune activation and future challenges
title_full_unstemmed COVID-19 vaccines: modes of immune activation and future challenges
title_short COVID-19 vaccines: modes of immune activation and future challenges
title_sort covid-19 vaccines: modes of immune activation and future challenges
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934118/
https://www.ncbi.nlm.nih.gov/pubmed/33674759
http://dx.doi.org/10.1038/s41577-021-00526-x
work_keys_str_mv AT teijarojohnr covid19vaccinesmodesofimmuneactivationandfuturechallenges
AT farberdonnal covid19vaccinesmodesofimmuneactivationandfuturechallenges

Ejemplares similares