HDAC inhibitors suppress the proliferation, migration and invasiveness of human head and neck squamous cell carcinoma cells via p63-mediated tight junction molecules and p21-mediated growth arrest

In human head and neck squamous cell carcinoma (HNSCC), the invasion and metastatic properties of cancer cells are promoted by junctional adhesion molecule-A (JAM-A) and claudin-1; these are epithelial tight junction molecules regulated by histone deacetylases (HDACs) and transcription factor p63. H...

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Detalles Bibliográficos
Autores principales: Kakiuchi, Akito, Kakuki, Takuya, Ohwada, Kizuku, Kurose, Makoto, Kondoh, Atsushi, Obata, Kazufumi, Nomura, Kazuaki, Miyata, Ryo, Kaneko, Yakuto, Konno, Takumi, Kohno, Takayuki, Himi, Tetsuo, Takano, Ken-Ichi, Kojima, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934225/
https://www.ncbi.nlm.nih.gov/pubmed/33649777
http://dx.doi.org/10.3892/or.2021.7997

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