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Prospective verification of sonographic fetal weight estimators among term parturients in Uganda

BACKGROUND: Accuracy of fetal weight estimation by ultrasound is essential in making decisions on the time and mode of delivery. There are many proposed formulas for fetal weight estimation such as Hadlock 1, Hadlock 2, Hadlock 3, Hadlock 4 and Shepard. What best applies to the Ugandan population is...

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Autores principales: Sereke, Senai Goitom, Omara, Richard Okello, Bongomin, Felix, Nakubulwa, Sarah, Kisembo, Harriet Nalubega
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934251/
https://www.ncbi.nlm.nih.gov/pubmed/33663407
http://dx.doi.org/10.1186/s12884-021-03645-4
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author Sereke, Senai Goitom
Omara, Richard Okello
Bongomin, Felix
Nakubulwa, Sarah
Kisembo, Harriet Nalubega
author_facet Sereke, Senai Goitom
Omara, Richard Okello
Bongomin, Felix
Nakubulwa, Sarah
Kisembo, Harriet Nalubega
author_sort Sereke, Senai Goitom
collection PubMed
description BACKGROUND: Accuracy of fetal weight estimation by ultrasound is essential in making decisions on the time and mode of delivery. There are many proposed formulas for fetal weight estimation such as Hadlock 1, Hadlock 2, Hadlock 3, Hadlock 4 and Shepard. What best applies to the Ugandan population is not known since no verification of any of the formulas has been done before. The primary aim of this study was to determine the accuracy of sonographic estimation of fetal weight using five most commonly used formulas, and analyze formula variations for different weight ranges. METHODS: This was a hospital based prospective cohort study at Mulago National Referral Hospital, Kampala, Uganda. A total of 356 pregnant women who consented and were within 3 days of birth were enrolled. Prenatal ultrasound fetal weight determined by measuring the biparietal diameter, head circumference, abdominal circumference, femoral length, and then was compared with actual birth weight. RESULTS: The overall accuracy of Hadlock 1, Hadlock 2, Hadlock 3, Hadlock 4 and Shepard formula were 66.9, 73.3, 77.3, 78.4 and 69.7% respectively. All Hadlocks showed significant mean difference between weight estimates and actual birth weight (p < 0.01) whereas Shepard formula did not [p - 0.2], when no stratification of fetal weights was done. However, all Hadlocks showed a none significant (p-values > 0.05) mean difference between weight estimates and actual birth weight when the actual birth weight was ≥4000.0 g. Shepard weight estimates showed a none significant mean difference when actual birth weight was < 4000 g. Bland-Altman graphs also showed a better agreement of weight estimated by Shepard formula and actual birth weights. CONCLUSION: All the five formulas were accurate at estimating actual birth weights within 10% accuracy. However, this accuracy varied with the fetal birth weight. Shepard was more accurate in estimating actual birth weights < 4000 g whereas all Hadlocks were more accurate when the actual birthweight was ≥4000 g. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12884-021-03645-4.
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spelling pubmed-79342512021-03-05 Prospective verification of sonographic fetal weight estimators among term parturients in Uganda Sereke, Senai Goitom Omara, Richard Okello Bongomin, Felix Nakubulwa, Sarah Kisembo, Harriet Nalubega BMC Pregnancy Childbirth Research Article BACKGROUND: Accuracy of fetal weight estimation by ultrasound is essential in making decisions on the time and mode of delivery. There are many proposed formulas for fetal weight estimation such as Hadlock 1, Hadlock 2, Hadlock 3, Hadlock 4 and Shepard. What best applies to the Ugandan population is not known since no verification of any of the formulas has been done before. The primary aim of this study was to determine the accuracy of sonographic estimation of fetal weight using five most commonly used formulas, and analyze formula variations for different weight ranges. METHODS: This was a hospital based prospective cohort study at Mulago National Referral Hospital, Kampala, Uganda. A total of 356 pregnant women who consented and were within 3 days of birth were enrolled. Prenatal ultrasound fetal weight determined by measuring the biparietal diameter, head circumference, abdominal circumference, femoral length, and then was compared with actual birth weight. RESULTS: The overall accuracy of Hadlock 1, Hadlock 2, Hadlock 3, Hadlock 4 and Shepard formula were 66.9, 73.3, 77.3, 78.4 and 69.7% respectively. All Hadlocks showed significant mean difference between weight estimates and actual birth weight (p < 0.01) whereas Shepard formula did not [p - 0.2], when no stratification of fetal weights was done. However, all Hadlocks showed a none significant (p-values > 0.05) mean difference between weight estimates and actual birth weight when the actual birth weight was ≥4000.0 g. Shepard weight estimates showed a none significant mean difference when actual birth weight was < 4000 g. Bland-Altman graphs also showed a better agreement of weight estimated by Shepard formula and actual birth weights. CONCLUSION: All the five formulas were accurate at estimating actual birth weights within 10% accuracy. However, this accuracy varied with the fetal birth weight. Shepard was more accurate in estimating actual birth weights < 4000 g whereas all Hadlocks were more accurate when the actual birthweight was ≥4000 g. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12884-021-03645-4. BioMed Central 2021-03-04 /pmc/articles/PMC7934251/ /pubmed/33663407 http://dx.doi.org/10.1186/s12884-021-03645-4 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Sereke, Senai Goitom
Omara, Richard Okello
Bongomin, Felix
Nakubulwa, Sarah
Kisembo, Harriet Nalubega
Prospective verification of sonographic fetal weight estimators among term parturients in Uganda
title Prospective verification of sonographic fetal weight estimators among term parturients in Uganda
title_full Prospective verification of sonographic fetal weight estimators among term parturients in Uganda
title_fullStr Prospective verification of sonographic fetal weight estimators among term parturients in Uganda
title_full_unstemmed Prospective verification of sonographic fetal weight estimators among term parturients in Uganda
title_short Prospective verification of sonographic fetal weight estimators among term parturients in Uganda
title_sort prospective verification of sonographic fetal weight estimators among term parturients in uganda
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934251/
https://www.ncbi.nlm.nih.gov/pubmed/33663407
http://dx.doi.org/10.1186/s12884-021-03645-4
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