Cargando…
The IL‐27/IL‐27R axis is altered in CD4(+) and CD8(+) T lymphocytes from multiple sclerosis patients
OBJECTIVES: Pro‐ and anti‐inflammatory properties have been attributed to interleukin‐27 (IL‐27). Nevertheless, the impact of this cytokine on chronic inflammatory diseases such as multiple sclerosis (MS) remains ill‐defined. We investigated the biology of IL‐27 and its specific receptor IL‐27Rα in...
Autores principales: | Clénet, Marie‐Laure, Laurent, Cyril, Lemaitre, Florent, Farzam‐kia, Negar, Tastet, Olivier, Devergne, Odile, Lahav, Boaz, Girard, Marc, Duquette, Pierre, Prat, Alexandre, Larochelle, Catherine, Arbour, Nathalie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934284/ https://www.ncbi.nlm.nih.gov/pubmed/33728050 http://dx.doi.org/10.1002/cti2.1262 |
Ejemplares similares
-
IL-27 shapes the immune properties of human astrocytes and their impact on encountered human T lymphocytes
por: Lemaître, Florent, et al.
Publicado: (2022) -
Interleukin-15 enhances proinflammatory T-cell responses in patients with MS and EAE
por: Laurent, Cyril, et al.
Publicado: (2020) -
Stress Signal ULBP4, an NKG2D Ligand, Is Upregulated in Multiple Sclerosis and Shapes CD8(+) T-Cell Behaviors
por: Carmena Moratalla, Ana, et al.
Publicado: (2021) -
Peripheral human CD4(+)CD8(+) T lymphocytes exhibit a memory phenotype and enhanced responses to IL-2, IL-7 and IL-15
por: Clénet, Marie-Laure, et al.
Publicado: (2017) -
Expression of IL-27 by Tumor Cells in InvasCutaneous and Metastatic Melanomas
por: Gonin, Julie, et al.
Publicado: (2013)