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Lipoprotein glomerulopathy induced by ApoE Kyoto mutation in ApoE-deficient mice

BACKGROUND: Lipoprotein glomerulopathy (LPG) is a rare autosomal dominant kidney disease that is most commonly caused by mutations in ApoE Kyoto (p.R43C) and ApoE Sendai (p.R163P). Differences in phenotype among the various ApoE mutations have been suggested, but the pathogenic role of ApoE Kyoto ha...

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Detalles Bibliográficos
Autores principales: Wu, Hongyan, Yang, Jing, Liu, Yun-Qiang, Lei, Song, Yang, Mei, Yang, Zhi, Yang, Yuan, Hu, Zhangxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934380/
https://www.ncbi.nlm.nih.gov/pubmed/33663537
http://dx.doi.org/10.1186/s12967-021-02765-x

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