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Lipoprotein glomerulopathy induced by ApoE Kyoto mutation in ApoE-deficient mice
BACKGROUND: Lipoprotein glomerulopathy (LPG) is a rare autosomal dominant kidney disease that is most commonly caused by mutations in ApoE Kyoto (p.R43C) and ApoE Sendai (p.R163P). Differences in phenotype among the various ApoE mutations have been suggested, but the pathogenic role of ApoE Kyoto ha...
Autores principales: | Wu, Hongyan, Yang, Jing, Liu, Yun-Qiang, Lei, Song, Yang, Mei, Yang, Zhi, Yang, Yuan, Hu, Zhangxue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934380/ https://www.ncbi.nlm.nih.gov/pubmed/33663537 http://dx.doi.org/10.1186/s12967-021-02765-x |
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