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Neural classification of Norwegian radiology reports: using NLP to detect findings in CT-scans of children

BACKGROUND: With a motivation of quality assurance, machine learning techniques were trained to classify Norwegian radiology reports of paediatric CT examinations according to their description of abnormal findings. METHODS: 13.506 reports from CT-scans of children, 1000 reports from CT scan of adul...

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Autores principales: Dahl, Fredrik A., Rama, Taraka, Hurlen, Petter, Brekke, Pål H., Husby, Haldor, Gundersen, Tore, Nytrø, Øystein, Øvrelid, Lilja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934405/
https://www.ncbi.nlm.nih.gov/pubmed/33663479
http://dx.doi.org/10.1186/s12911-021-01451-8
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author Dahl, Fredrik A.
Rama, Taraka
Hurlen, Petter
Brekke, Pål H.
Husby, Haldor
Gundersen, Tore
Nytrø, Øystein
Øvrelid, Lilja
author_facet Dahl, Fredrik A.
Rama, Taraka
Hurlen, Petter
Brekke, Pål H.
Husby, Haldor
Gundersen, Tore
Nytrø, Øystein
Øvrelid, Lilja
author_sort Dahl, Fredrik A.
collection PubMed
description BACKGROUND: With a motivation of quality assurance, machine learning techniques were trained to classify Norwegian radiology reports of paediatric CT examinations according to their description of abnormal findings. METHODS: 13.506 reports from CT-scans of children, 1000 reports from CT scan of adults and 1000 reports from X-ray examination of adults were classified as positive or negative by a radiologist, according to the presence of abnormal findings. Inter-rater reliability was evaluated by comparison with a clinician’s classifications of 500 reports. Test–retest reliability of the radiologist was performed on the same 500 reports. A convolutional neural network model (CNN), a bidirectional recurrent neural network model (bi-LSTM) and a support vector machine model (SVM) were trained on a random selection of the children’s data set. Models were evaluated on the remaining CT-children reports and the adult data sets. RESULTS: Test–retest reliability: Cohen’s Kappa = 0.86 and F1 = 0.919. Inter-rater reliability: Kappa = 0.80 and F1 = 0.885. Model performances on the Children-CT data were as follows. CNN: (AUC = 0.981, F1 = 0.930), bi-LSTM: (AUC = 0.978, F1 = 0.927), SVM: (AUC = 0.975, F1 = 0.912). On the adult data sets, the models had AUC around 0.95 and F1 around 0.91. CONCLUSIONS: The models performed close to perfectly on its defined domain, and also performed convincingly on reports pertaining to a different patient group and a different modality. The models were deemed suitable for classifying radiology reports for future quality assurance purposes, where the fraction of the examinations with abnormal findings for different sub-groups of patients is a parameter of interest.
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spelling pubmed-79344052021-03-08 Neural classification of Norwegian radiology reports: using NLP to detect findings in CT-scans of children Dahl, Fredrik A. Rama, Taraka Hurlen, Petter Brekke, Pål H. Husby, Haldor Gundersen, Tore Nytrø, Øystein Øvrelid, Lilja BMC Med Inform Decis Mak Research Article BACKGROUND: With a motivation of quality assurance, machine learning techniques were trained to classify Norwegian radiology reports of paediatric CT examinations according to their description of abnormal findings. METHODS: 13.506 reports from CT-scans of children, 1000 reports from CT scan of adults and 1000 reports from X-ray examination of adults were classified as positive or negative by a radiologist, according to the presence of abnormal findings. Inter-rater reliability was evaluated by comparison with a clinician’s classifications of 500 reports. Test–retest reliability of the radiologist was performed on the same 500 reports. A convolutional neural network model (CNN), a bidirectional recurrent neural network model (bi-LSTM) and a support vector machine model (SVM) were trained on a random selection of the children’s data set. Models were evaluated on the remaining CT-children reports and the adult data sets. RESULTS: Test–retest reliability: Cohen’s Kappa = 0.86 and F1 = 0.919. Inter-rater reliability: Kappa = 0.80 and F1 = 0.885. Model performances on the Children-CT data were as follows. CNN: (AUC = 0.981, F1 = 0.930), bi-LSTM: (AUC = 0.978, F1 = 0.927), SVM: (AUC = 0.975, F1 = 0.912). On the adult data sets, the models had AUC around 0.95 and F1 around 0.91. CONCLUSIONS: The models performed close to perfectly on its defined domain, and also performed convincingly on reports pertaining to a different patient group and a different modality. The models were deemed suitable for classifying radiology reports for future quality assurance purposes, where the fraction of the examinations with abnormal findings for different sub-groups of patients is a parameter of interest. BioMed Central 2021-03-04 /pmc/articles/PMC7934405/ /pubmed/33663479 http://dx.doi.org/10.1186/s12911-021-01451-8 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Dahl, Fredrik A.
Rama, Taraka
Hurlen, Petter
Brekke, Pål H.
Husby, Haldor
Gundersen, Tore
Nytrø, Øystein
Øvrelid, Lilja
Neural classification of Norwegian radiology reports: using NLP to detect findings in CT-scans of children
title Neural classification of Norwegian radiology reports: using NLP to detect findings in CT-scans of children
title_full Neural classification of Norwegian radiology reports: using NLP to detect findings in CT-scans of children
title_fullStr Neural classification of Norwegian radiology reports: using NLP to detect findings in CT-scans of children
title_full_unstemmed Neural classification of Norwegian radiology reports: using NLP to detect findings in CT-scans of children
title_short Neural classification of Norwegian radiology reports: using NLP to detect findings in CT-scans of children
title_sort neural classification of norwegian radiology reports: using nlp to detect findings in ct-scans of children
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934405/
https://www.ncbi.nlm.nih.gov/pubmed/33663479
http://dx.doi.org/10.1186/s12911-021-01451-8
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