Development of a chitosan‐modified PLGA nanoparticle vaccine for protection against Escherichia coli K1 caused meningitis in mice

BACKGROUND: Escherichia coli K1 (E. coli K1) caused neonatal meningitis remains a problem, which rises the urgent need for an effective vaccine. Previously, we rationally designed and produced the recombinant protein OmpAVac (Vo), which elicited protective immunity against E. coli K1 infection. Howe...

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Detalles Bibliográficos
Autores principales: Zhang, Jin, Sun, Hongwu, Gao, Chen, Wang, Ying, Cheng, Xin, Yang, Yun, Gou, Qiang, Lei, Langhuang, Chen, Yanping, Wang, Xingyong, Zou, Quanming, Gu, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934409/
https://www.ncbi.nlm.nih.gov/pubmed/33673858
http://dx.doi.org/10.1186/s12951-021-00812-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934409/
https://www.ncbi.nlm.nih.gov/pubmed/33673858
http://dx.doi.org/10.1186/s12951-021-00812-9

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