Enhancing GABAergic signaling ameliorates aberrant gamma oscillations of olfactory bulb in AD mouse models

BACKGROUND: Before the deposition of amyloid-beta plaques and the onset of learning memory deficits, patients with Alzheimer’s disease (AD) experience olfactory dysfunction, typified by a reduced ability to detect, discriminate, and identify odors. Rodent models of AD, such as the Tg2576 and APP/PS1...

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Detalles Bibliográficos
Autores principales: Chen, Ming, Chen, Yunan, Huo, Qingwei, Wang, Lei, Tan, Shuyi, Misrani, Afzal, Jiang, Jinxiang, Chen, Jian, Chen, Shiyuan, Zhang, Jiawei, Tabassum, Sidra, Wang, Jichen, Chen, Xi, Long, Cheng, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934466/
https://www.ncbi.nlm.nih.gov/pubmed/33663578
http://dx.doi.org/10.1186/s13024-021-00434-7

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