Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity

BACKGROUND: Many neurodegenerative diseases develop only later in life, when cells in the nervous system lose their structure or function. In many forms of neurodegenerative diseases, this late-onset phenomenon remains largely unexplained. RESULTS: Analyzing single-cell RNA sequencing from Alzheimer...

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Detalles Bibliográficos
Autores principales: Sorek, Matan, Oweis, Walaa, Nissim-Rafinia, Malka, Maman, Moria, Simon, Shahar, Hession, Cynthia C., Adiconis, Xian, Simmons, Sean K., Sanjana, Neville E., Shi, Xi, Lu, Congyi, Pan, Jen Q., Xu, Xiaohong, Pouladi, Mahmoud A., Ellerby, Lisa M., Zhang, Feng, Levin, Joshua Z., Meshorer, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934477/
https://www.ncbi.nlm.nih.gov/pubmed/33663567
http://dx.doi.org/10.1186/s13059-021-02301-6

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