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A feasibility study evaluating a reservoir storage system for continuous oxygen delivery for children with hypoxemia in Kenya

BACKGROUND: Supplemental oxygen is an essential treatment for childhood pneumonia but is often unavailable in low-resource settings or unreliable due to frequent and long-lasting power outages. We present a novel medium pressure reservoir (MPR) which delivers continuous oxygen to pediatric patients...

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Autores principales: Otiangala, Dickson, Agai, Nicholas O., Olayo, Bernard, Adudans, Steve, Ng, Chin Hei, Calderon, Ryan, Forgie, Ella, Bachman, Christine, Lieberman, Daniel, Bell, David, Hawkes, Michael, Somoskovi, Akos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934496/
https://www.ncbi.nlm.nih.gov/pubmed/33663453
http://dx.doi.org/10.1186/s12890-021-01433-6
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author Otiangala, Dickson
Agai, Nicholas O.
Olayo, Bernard
Adudans, Steve
Ng, Chin Hei
Calderon, Ryan
Forgie, Ella
Bachman, Christine
Lieberman, Daniel
Bell, David
Hawkes, Michael
Somoskovi, Akos
author_facet Otiangala, Dickson
Agai, Nicholas O.
Olayo, Bernard
Adudans, Steve
Ng, Chin Hei
Calderon, Ryan
Forgie, Ella
Bachman, Christine
Lieberman, Daniel
Bell, David
Hawkes, Michael
Somoskovi, Akos
author_sort Otiangala, Dickson
collection PubMed
description BACKGROUND: Supplemental oxygen is an essential treatment for childhood pneumonia but is often unavailable in low-resource settings or unreliable due to frequent and long-lasting power outages. We present a novel medium pressure reservoir (MPR) which delivers continuous oxygen to pediatric patients through power outages. METHODS: An observational case series pilot study assessing the capacity, efficacy and user appraisal of a novel MPR device for use in low-resource pediatric wards. We designed and tested a MPR in a controlled preclinical setting, established feasibility of the device in two rural Kenyan hospitals, and sought user feedback and satisfaction using a standardized questionnaire. RESULTS: Preclinical data showed that the MPR was capable of bridging power outages and delivering a continuous flow of oxygen to a simulated patient. The MPR was then deployed for clinical testing in nine pediatric patients at Ahero and Suba Hospitals. Power was unavailable for 2% of the total time observed due to 11 power outages (median 4.6 min, IQR 3.6–13.0 min) that occurred during treatment with the MPR. Oxygen flowrates remained constant across all 11 power outages. Feedback on the MPR was uniformly positive; all respondents indicated that the MPR was easy to use and provided clinically significant help to their patients. CONCLUSION: We present a MPR oxygen delivery device that has the potential to mitigate power insecurity and improve the standard of care for hypoxemic pediatric patients in resource-limited settings. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12890-021-01433-6.
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spelling pubmed-79344962021-03-08 A feasibility study evaluating a reservoir storage system for continuous oxygen delivery for children with hypoxemia in Kenya Otiangala, Dickson Agai, Nicholas O. Olayo, Bernard Adudans, Steve Ng, Chin Hei Calderon, Ryan Forgie, Ella Bachman, Christine Lieberman, Daniel Bell, David Hawkes, Michael Somoskovi, Akos BMC Pulm Med Article BACKGROUND: Supplemental oxygen is an essential treatment for childhood pneumonia but is often unavailable in low-resource settings or unreliable due to frequent and long-lasting power outages. We present a novel medium pressure reservoir (MPR) which delivers continuous oxygen to pediatric patients through power outages. METHODS: An observational case series pilot study assessing the capacity, efficacy and user appraisal of a novel MPR device for use in low-resource pediatric wards. We designed and tested a MPR in a controlled preclinical setting, established feasibility of the device in two rural Kenyan hospitals, and sought user feedback and satisfaction using a standardized questionnaire. RESULTS: Preclinical data showed that the MPR was capable of bridging power outages and delivering a continuous flow of oxygen to a simulated patient. The MPR was then deployed for clinical testing in nine pediatric patients at Ahero and Suba Hospitals. Power was unavailable for 2% of the total time observed due to 11 power outages (median 4.6 min, IQR 3.6–13.0 min) that occurred during treatment with the MPR. Oxygen flowrates remained constant across all 11 power outages. Feedback on the MPR was uniformly positive; all respondents indicated that the MPR was easy to use and provided clinically significant help to their patients. CONCLUSION: We present a MPR oxygen delivery device that has the potential to mitigate power insecurity and improve the standard of care for hypoxemic pediatric patients in resource-limited settings. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12890-021-01433-6. BioMed Central 2021-03-05 /pmc/articles/PMC7934496/ /pubmed/33663453 http://dx.doi.org/10.1186/s12890-021-01433-6 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Article
Otiangala, Dickson
Agai, Nicholas O.
Olayo, Bernard
Adudans, Steve
Ng, Chin Hei
Calderon, Ryan
Forgie, Ella
Bachman, Christine
Lieberman, Daniel
Bell, David
Hawkes, Michael
Somoskovi, Akos
A feasibility study evaluating a reservoir storage system for continuous oxygen delivery for children with hypoxemia in Kenya
title A feasibility study evaluating a reservoir storage system for continuous oxygen delivery for children with hypoxemia in Kenya
title_full A feasibility study evaluating a reservoir storage system for continuous oxygen delivery for children with hypoxemia in Kenya
title_fullStr A feasibility study evaluating a reservoir storage system for continuous oxygen delivery for children with hypoxemia in Kenya
title_full_unstemmed A feasibility study evaluating a reservoir storage system for continuous oxygen delivery for children with hypoxemia in Kenya
title_short A feasibility study evaluating a reservoir storage system for continuous oxygen delivery for children with hypoxemia in Kenya
title_sort feasibility study evaluating a reservoir storage system for continuous oxygen delivery for children with hypoxemia in kenya
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934496/
https://www.ncbi.nlm.nih.gov/pubmed/33663453
http://dx.doi.org/10.1186/s12890-021-01433-6
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