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lnc-MAP3K13-7:1 Inhibits Ovarian GC Proliferation in PCOS via DNMT1 Downregulation-Mediated CDKN1A Promoter Hypomethylation
Polycystic ovary syndrome (PCOS) is an endocrine-related disease and global cause of infertility that is associated with abnormal folliculogenesis. Inhibited granulosa cell (GC) proliferation is recognized as a key factor that underlies aberrant follicle maturation. Many epigenetic landscape modific...
Autores principales: | Geng, Xueying, Zhao, Jun, Huang, Jiayu, Li, Shang, Chu, Weiwei, Wang, Wang-sheng, Chen, Zi-Jiang, Du, Yanzhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934583/ https://www.ncbi.nlm.nih.gov/pubmed/33212300 http://dx.doi.org/10.1016/j.ymthe.2020.11.018 |
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