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Blood donor exposome and impact of common drugs on red blood cell metabolism

Computational models based on recent maps of the RBC proteome suggest that mature erythrocytes may harbor targets for common drugs. This prediction is relevant to RBC storage in the blood bank, in which the impact of small molecule drugs or other xenometabolites deriving from dietary, iatrogenic, or...

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Detalles Bibliográficos
Autores principales: Nemkov, Travis, Stefanoni, Davide, Bordbar, Aarash, Issaian, Aaron, Palsson, Bernhard O., Dumont, Larry J., Hay, Ariel, Song, Anren, Xia, Yang, Redzic, Jasmina S., Eisenmesser, Elan Z., Zimring, James C., Kleinman, Steve, Hansen, Kirk C., Busch, Michael P., D’Alessandro, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934844/
https://www.ncbi.nlm.nih.gov/pubmed/33351786
http://dx.doi.org/10.1172/jci.insight.146175