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Tregs facilitate obesity and insulin resistance via a Blimp-1/IL-10 axis

Interleukin-10 (IL-10) is a critical cytokine used by immune cells to suppress inflammation. Paradoxically, immune cell–derived IL-10 can drive insulin resistance in obesity by suppressing adipocyte energy expenditure and thermogenesis. However, the source of IL-10 necessary for the suppression of a...

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Detalles Bibliográficos
Autores principales:	Beppu, Lisa Y., Mooli, Raja Gopal Reddy, Qu, Xiaoyao, Marrero, Giovanni J., Finley, Christopher A., Fooks, Allen N., Mullen, Zackary P., Frias, Adolfo B., Sipula, Ian, Xie, Bingxian, Helfrich, Katherine E., Watkins, Simon C., Poholek, Amanda C., Ramakrishnan, Sadeesh K., Jurczak, Michael J., D’Cruz, Louise M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934851/ https://www.ncbi.nlm.nih.gov/pubmed/33351782 http://dx.doi.org/10.1172/jci.insight.140644

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