STING activation in alveolar macrophages and group 2 innate lymphoid cells suppresses IL-33–driven type 2 immunopathology

2′3′-cGAMP is known as a nonclassical second messenger and small immune modulator that possesses potent antitumor and antiviral activities via inducing the stimulator of IFN genes–mediated (STING-mediated) signaling pathway. However, its function in regulating type 2 immune responses remains unknown...

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Detalles Bibliográficos
Autores principales: She, Li, Barrera, Gema D., Yan, Liping, Alanazi, Hamad H., Brooks, Edward G., Dube, Peter H., Sun, Yilun, Zan, Hong, Chupp, Daniel P., Zhang, Nu, Zhang, Xin, Liu, Yong, Li, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934858/
https://www.ncbi.nlm.nih.gov/pubmed/33400692
http://dx.doi.org/10.1172/jci.insight.143509

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