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Stem cell transplantation uncovers TDO-AHR regulation of lung dendritic cells in herpesvirus-induced pathology

The aryl-hydrocarbon receptor (AHR) is an intracellular sensor of aromatic hydrocarbons that sits at the top of various immunomodulatory pathways. Here, we present evidence that AHR plays a role in controlling IL-17 responses and the development of pulmonary fibrosis in response to respiratory patho...

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Detalles Bibliográficos
Autores principales: Gurczynski, Stephen J., Pereira, Nicolas L., Hrycaj, Steven M., Wilke, Carol, Zemans, Rachel L., Moore, Bethany B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934859/
https://www.ncbi.nlm.nih.gov/pubmed/33491663
http://dx.doi.org/10.1172/jci.insight.139965