HIV-specific T cell responses reflect substantive in vivo interactions with antigen despite long-term therapy

Antiretroviral therapies (ARTs) abrogate HIV replication; however, infection persists as long-lived reservoirs of infected cells with integrated proviruses, which reseed replication if ART is interrupted. A central tenet of our current understanding of this persistence is that infected cells are shi...

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Detalles Bibliográficos
Autores principales: Stevenson, Eva M., Ward, Adam R., Truong, Ronald, Thomas, Allison S., Huang, Szu-Han, Dilling, Thomas R., Terry, Sandra, Bui, John K., Mota, Talia M., Danesh, Ali, Lee, Guinevere Q., Gramatica, Andrea, Khadka, Pragya, Alberto, Winiffer D. Conce, Gandhi, Rajesh T., McMahon, Deborah K., Lalama, Christina M., Bosch, Ronald J., Macatangay, Bernard, Cyktor, Joshua C., Eron, Joseph J., Mellors, John W., Jones, R. Brad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934865/
https://www.ncbi.nlm.nih.gov/pubmed/33400687
http://dx.doi.org/10.1172/jci.insight.142640

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