Cargando…
Potent antitumor effects of cell-penetrating peptides targeting STAT3 axis
To date, there are no inhibitors that directly and specifically target activated STAT3 and c-Myc in the clinic. Although peptide-based inhibitors can selectively block activated targets, their clinical usage is limited because of low cell penetration and/or serum stability. Here, we generated cell-p...
Autores principales: | Aftabizadeh, Maryam, Li, Yi-Jia, Zhao, Qianqian, Zhang, Chunyan, Ambaye, Nigus, Song, Jieun, Nagao, Toshikage, Lahtz, Christoph, Fakih, Marwan, Ann, David K., Yu, Hua, Herrmann, Andreas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934871/ https://www.ncbi.nlm.nih.gov/pubmed/33491667 http://dx.doi.org/10.1172/jci.insight.136176 |
Ejemplares similares
-
Integrin α6 signaling induces STAT3-TET3-mediated hydroxymethylation of genes critical for maintenance of glioma stem cells
por: Herrmann, Andreas, et al.
Publicado: (2019) -
Cationic Cell-Penetrating Peptides Are Potent Furin Inhibitors
por: Ramos-Molina, Bruno, et al.
Publicado: (2015) -
Lycorine Displays Potent Antitumor Efficacy in Colon Carcinoma by Targeting STAT3
por: Wu, Song, et al.
Publicado: (2018) -
Cell penetrating peptide: A potent delivery system in vaccine development
por: Hasannejad-Asl, Behnam, et al.
Publicado: (2022) -
Synthesis and biological evaluation of celastrol derivatives as potent antitumor agents with STAT3 inhibition
por: Xu, Shaohua, et al.
Publicado: (2021)