A road map from single-cell transcriptome to patient classification for the immune response to trauma

Immune dysfunction is an important factor driving mortality and adverse outcomes after trauma but remains poorly understood, especially at the cellular level. To deconvolute the trauma-induced immune response, we applied single-cell RNA sequencing to circulating and bone marrow mononuclear cells in...

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Detalles Bibliográficos
Autores principales: Chen, Tianmeng, Delano, Matthew J., Chen, Kong, Sperry, Jason L., Namas, Rami A., Lamparello, Ashley J., Deng, Meihong, Conroy, Julia, Moldawer, Lyle L., Efron, Philip A., Loughran, Patricia, Seymour, Christopher, Angus, Derek C., Vodovotz, Yoram, Chen, Wei, Billiar, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934885/
https://www.ncbi.nlm.nih.gov/pubmed/33320841
http://dx.doi.org/10.1172/jci.insight.145108

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