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Wavelength-specific optoacoustic-induced vibrations of the guinea pig tympanic membrane

Significance: Optoacoustic-induced vibrations of the hearing organ can potentially be used for a hearing device. To increase the efficiency of such a hearing device, the conversion of the light energy into vibration energy within each type of irradiated tissue has to be optimized. Aim: To analyze th...

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Autores principales: Heimann, Larissa, Carlein, Christopher, Sorg, Katharina, Diller, Rolf, Langenbucher, Achim, Schick, Bernhard, Wenzel, Gentiana Ioana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934890/
https://www.ncbi.nlm.nih.gov/pubmed/33675190
http://dx.doi.org/10.1117/1.JBO.26.3.038001
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author Heimann, Larissa
Carlein, Christopher
Sorg, Katharina
Diller, Rolf
Langenbucher, Achim
Schick, Bernhard
Wenzel, Gentiana Ioana
author_facet Heimann, Larissa
Carlein, Christopher
Sorg, Katharina
Diller, Rolf
Langenbucher, Achim
Schick, Bernhard
Wenzel, Gentiana Ioana
author_sort Heimann, Larissa
collection PubMed
description Significance: Optoacoustic-induced vibrations of the hearing organ can potentially be used for a hearing device. To increase the efficiency of such a hearing device, the conversion of the light energy into vibration energy within each type of irradiated tissue has to be optimized. Aim: To analyze the wavelength-dependency of optoacoustic-induced vibrations within the tympanic membrane (TM), and to define the most efficient and best-suited optical stimulation parameters for a novel auditory prosthesis. Approach: Single nanosecond laser pulses, continuously tunable in a range of visible to near-infrared, were used to excite the guinea pig TM. The induced vibrations of the hearing organ were recorded at the malleus using a laser Doppler vibrometer. Results: Our results indicate a strong wavelength-dependency of the vibration’s amplitude correlating with the superposition of the absorption spectra of the different specific tissue components. Conclusions: We investigated the spectrum of the vibrations of the hearing organ that were induced optoacoustically within a biological membrane embedded in air, in an animal model. First applications for these results can be envisioned for the optical stimulation of the peripheral hearing organ as well as for research purposes.
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spelling pubmed-79348902021-03-05 Wavelength-specific optoacoustic-induced vibrations of the guinea pig tympanic membrane Heimann, Larissa Carlein, Christopher Sorg, Katharina Diller, Rolf Langenbucher, Achim Schick, Bernhard Wenzel, Gentiana Ioana J Biomed Opt Therapeutic Significance: Optoacoustic-induced vibrations of the hearing organ can potentially be used for a hearing device. To increase the efficiency of such a hearing device, the conversion of the light energy into vibration energy within each type of irradiated tissue has to be optimized. Aim: To analyze the wavelength-dependency of optoacoustic-induced vibrations within the tympanic membrane (TM), and to define the most efficient and best-suited optical stimulation parameters for a novel auditory prosthesis. Approach: Single nanosecond laser pulses, continuously tunable in a range of visible to near-infrared, were used to excite the guinea pig TM. The induced vibrations of the hearing organ were recorded at the malleus using a laser Doppler vibrometer. Results: Our results indicate a strong wavelength-dependency of the vibration’s amplitude correlating with the superposition of the absorption spectra of the different specific tissue components. Conclusions: We investigated the spectrum of the vibrations of the hearing organ that were induced optoacoustically within a biological membrane embedded in air, in an animal model. First applications for these results can be envisioned for the optical stimulation of the peripheral hearing organ as well as for research purposes. Society of Photo-Optical Instrumentation Engineers 2021-03-05 2021-03 /pmc/articles/PMC7934890/ /pubmed/33675190 http://dx.doi.org/10.1117/1.JBO.26.3.038001 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/ Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
spellingShingle Therapeutic
Heimann, Larissa
Carlein, Christopher
Sorg, Katharina
Diller, Rolf
Langenbucher, Achim
Schick, Bernhard
Wenzel, Gentiana Ioana
Wavelength-specific optoacoustic-induced vibrations of the guinea pig tympanic membrane
title Wavelength-specific optoacoustic-induced vibrations of the guinea pig tympanic membrane
title_full Wavelength-specific optoacoustic-induced vibrations of the guinea pig tympanic membrane
title_fullStr Wavelength-specific optoacoustic-induced vibrations of the guinea pig tympanic membrane
title_full_unstemmed Wavelength-specific optoacoustic-induced vibrations of the guinea pig tympanic membrane
title_short Wavelength-specific optoacoustic-induced vibrations of the guinea pig tympanic membrane
title_sort wavelength-specific optoacoustic-induced vibrations of the guinea pig tympanic membrane
topic Therapeutic
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934890/
https://www.ncbi.nlm.nih.gov/pubmed/33675190
http://dx.doi.org/10.1117/1.JBO.26.3.038001
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