Circulating mitochondrial DNA is an early indicator of severe illness and mortality from COVID-19

BACKGROUND: Mitochondrial DNA (MT-DNA) are intrinsically inflammatory nucleic acids released by damaged solid organs. Whether circulating cell-free MT-DNA quantitation could be used to predict the risk of poor COVID-19 outcomes remains undetermined. METHODS: We measured circulating MT-DNA levels in...

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Detalles Bibliográficos
Autores principales: Scozzi, Davide, Cano, Marlene, Ma, Lina, Zhou, Dequan, Zhu, Ji Hong, O’Halloran, Jane A., Goss, Charles, Rauseo, Adriana M., Liu, Zhiyi, Sahu, Sanjaya K., Peritore, Valentina, Rocco, Monica, Ricci, Alberto, Amodeo, Rachele, Aimati, Laura, Ibrahim, Mohsen, Hachem, Ramsey, Kreisel, Daniel, Mudd, Philip A., Kulkarni, Hrishikesh S., Gelman, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934921/
https://www.ncbi.nlm.nih.gov/pubmed/33444289
http://dx.doi.org/10.1172/jci.insight.143299

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