Immunopathogenic CSF TCR repertoire signatures in virus-associated neurologic disease

In this study, we examined and characterized disease-specific TCR signatures in cerebrospinal fluid (CSF) of patients with HTLV-1–associated myelopathy/tropical spastic paraparesis (HAM/TSP). TCR β libraries using unique molecular identifier–based methodologies were sequenced in paired peripheral bl...

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Detalles Bibliográficos
Autores principales: Nozuma, Satoshi, Enose-Akahata, Yoshimi, Johnson, Kory R., Monaco, Maria Chiara, Ngouth, Nyater, Elkahloun, Abdel, Ohayon, Joan, Zhu, Jun, Jacobson, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934934/
https://www.ncbi.nlm.nih.gov/pubmed/33616082
http://dx.doi.org/10.1172/jci.insight.144869

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