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The Na(+), K(+)-ATPase β1 subunit regulates epithelial tight junctions via MRCKα

An intact lung epithelial barrier is essential for lung homeostasis. The Na(+), K(+)-ATPase (NKA), primarily serving as an ion transporter, also regulates epithelial barrier function via modulation of tight junctions. However, the underlying mechanism is not well understood. Here, we show that overe...

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Detalles Bibliográficos
Autores principales: Bai, Haiqing, Zhou, Rui, Barravecchia, Michael, Norman, Rosemary, Friedman, Alan, Yu, Deborah, Lin, Xin, Young, Jennifer L., Dean, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934944/
https://www.ncbi.nlm.nih.gov/pubmed/33507884
http://dx.doi.org/10.1172/jci.insight.134881