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Guillain-Barre Syndrome Associated With COVID-19 Infection: A Case Report With Review of Literature

COVID-19 has become a pandemic. It affects multiple systems of the body including the nervous system. It invades the nervous systems through multiple routes - either olfactory tract, bloodstream (by binding to endothelial receptors) or via ACE-2 receptors in the brain. We report a case of Guillain-B...

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Autores principales: Meshref, Mostafa, A. Alshammari, Hessa, Khairat, Shiamaa M, Khan, Roohi, Khan, Imran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935237/
https://www.ncbi.nlm.nih.gov/pubmed/33728118
http://dx.doi.org/10.7759/cureus.13096
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author Meshref, Mostafa
A. Alshammari, Hessa
Khairat, Shiamaa M
Khan, Roohi
Khan, Imran
author_facet Meshref, Mostafa
A. Alshammari, Hessa
Khairat, Shiamaa M
Khan, Roohi
Khan, Imran
author_sort Meshref, Mostafa
collection PubMed
description COVID-19 has become a pandemic. It affects multiple systems of the body including the nervous system. It invades the nervous systems through multiple routes - either olfactory tract, bloodstream (by binding to endothelial receptors) or via ACE-2 receptors in the brain. We report a case of Guillain-Barré syndrome (GBS) variant (acute motor axonal neuropathy (AMAN type)) associated with COVID-19 infection with positive polymerase chain reaction (PCR) test for COVID-19 and positive contact history with infected family member. GBS and its variants like AMAN can occur due to COVID-19 infection through its immune-mediated effects. Diagnosis of GBS should depend on the clinical and supportive criteria. The treatment should be started early to prevent progression and disease co-morbidities.
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spelling pubmed-79352372021-03-15 Guillain-Barre Syndrome Associated With COVID-19 Infection: A Case Report With Review of Literature Meshref, Mostafa A. Alshammari, Hessa Khairat, Shiamaa M Khan, Roohi Khan, Imran Cureus Neurology COVID-19 has become a pandemic. It affects multiple systems of the body including the nervous system. It invades the nervous systems through multiple routes - either olfactory tract, bloodstream (by binding to endothelial receptors) or via ACE-2 receptors in the brain. We report a case of Guillain-Barré syndrome (GBS) variant (acute motor axonal neuropathy (AMAN type)) associated with COVID-19 infection with positive polymerase chain reaction (PCR) test for COVID-19 and positive contact history with infected family member. GBS and its variants like AMAN can occur due to COVID-19 infection through its immune-mediated effects. Diagnosis of GBS should depend on the clinical and supportive criteria. The treatment should be started early to prevent progression and disease co-morbidities. Cureus 2021-02-03 /pmc/articles/PMC7935237/ /pubmed/33728118 http://dx.doi.org/10.7759/cureus.13096 Text en Copyright © 2021, Meshref et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Meshref, Mostafa
A. Alshammari, Hessa
Khairat, Shiamaa M
Khan, Roohi
Khan, Imran
Guillain-Barre Syndrome Associated With COVID-19 Infection: A Case Report With Review of Literature
title Guillain-Barre Syndrome Associated With COVID-19 Infection: A Case Report With Review of Literature
title_full Guillain-Barre Syndrome Associated With COVID-19 Infection: A Case Report With Review of Literature
title_fullStr Guillain-Barre Syndrome Associated With COVID-19 Infection: A Case Report With Review of Literature
title_full_unstemmed Guillain-Barre Syndrome Associated With COVID-19 Infection: A Case Report With Review of Literature
title_short Guillain-Barre Syndrome Associated With COVID-19 Infection: A Case Report With Review of Literature
title_sort guillain-barre syndrome associated with covid-19 infection: a case report with review of literature
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935237/
https://www.ncbi.nlm.nih.gov/pubmed/33728118
http://dx.doi.org/10.7759/cureus.13096
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