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Antibody affinity versus dengue morphology influences neutralization

Different strains within a dengue serotype (DENV1-4) can have smooth, or “bumpy” surface morphologies with different antigenic characteristics at average body temperature (37°C). We determined the neutralizing properties of a serotype cross-reactive human monoclonal antibody (HMAb) 1C19 for strains...

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Detalles Bibliográficos
Autores principales:	Fibriansah, Guntur, Lim, Elisa X. Y., Marzinek, Jan K., Ng, Thiam-Seng, Tan, Joanne L., Huber, Roland G., Lim, Xin-Ni, Chew, Valerie S. Y., Kostyuchenko, Victor A., Shi, Jian, Anand, Ganesh S., Bond, Peter J., Crowe, James E., Lok, Shee-Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935256/ https://www.ncbi.nlm.nih.gov/pubmed/33621239 http://dx.doi.org/10.1371/journal.ppat.1009331

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