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Genetic ablation of fibroblast activation protein alpha attenuates left ventricular dilation after myocardial infarction
INTRODUCTION: Regulating excessive activation of fibroblasts may be a promising target to optimize extracellular matrix deposition and myocardial stiffness. Fibroblast activation protein alpha (FAP) is upregulated in activated fibroblasts after myocardial infarction (MI), and alters fibroblast migra...
Autores principales: | Hoffmann, Daniel B., Fraccarollo, Daniela, Galuppo, Paolo, Frantz, Stefan, Bauersachs, Johann, Tillmanns, Jochen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935287/ https://www.ncbi.nlm.nih.gov/pubmed/33667270 http://dx.doi.org/10.1371/journal.pone.0248196 |
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