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Silencing of SRRM4 suppresses microexon inclusion and promotes tumor growth across cancers

RNA splicing is widely dysregulated in cancer, frequently due to altered expression or activity of splicing factors (SFs). Microexons are extremely small exons (3–27 nucleotides long) that are highly evolutionarily conserved and play critical roles in promoting neuronal differentiation and developme...

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Detalles Bibliográficos
Autores principales:	Head, Sarah A., Hernandez-Alias, Xavier, Yang, Jae-Seong, Ciampi, Ludovica, Beltran-Sastre, Violeta, Torres-Méndez, Antonio, Irimia, Manuel, Schaefer, Martin H., Serrano, Luis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935315/ https://www.ncbi.nlm.nih.gov/pubmed/33621242 http://dx.doi.org/10.1371/journal.pbio.3001138

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