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Biological Behavior and Lipid Metabolism of Colon Cancer Cells are Regulated by a Combination of Sterol Regulatory Element-Binding Protein 1 and ATP Citrate Lyase

PURPOSE: To research the effects of ATP citrate lyase (ACLY) and Sterol-regulatory element binding protein 1 (SREBP1) on the biology and lipid metabolism of colorectal cancer cells. METHODS: Colorectal cancer cells Caco-2 and Lovo were transfected with ACLY or SREBP1 gene knockdown lentiviruses. Fou...

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Detalles Bibliográficos
Autores principales:	Qiu, Zhendong, Deng, Wenhong, Hong, Yupu, Zhao, Liang, Li, Man, Guan, Yongjun, Su, Yingru, Chen, Chen, Shi, Qiao, Yu, Jia, Wang, Weixing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935446/ https://www.ncbi.nlm.nih.gov/pubmed/33688201 http://dx.doi.org/10.2147/OTT.S282906

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