Immune Regulation of the cGAS-STING Signaling Pathway in the Tumor Microenvironment and Its Clinical Application

As a DNA receptor in the cytoplasm, cyclic GMP-AMP synthase (cGAS) contributes to the recognition of abnormal DNA in the cytoplasm and contributes to the stimulator of interferon genes (STING) signaling pathway. cGAS could mediate the expression of interferon-related genes, inflammatory-related fact...

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Detalles Bibliográficos
Autores principales: Pu, Feifei, Chen, Fengxia, Liu, Jianxiang, Zhang, Zhicai, Shao, Zengwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935450/
https://www.ncbi.nlm.nih.gov/pubmed/33688199
http://dx.doi.org/10.2147/OTT.S298958

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