Case Report: Post-mortem Histopathological and Molecular Analyses of the Very First Documented COVID-19-Related Death in Europe

In Europe, the first case of coronavirus disease (COVID-19) and the first COVID-19-related death were reported in France on January 24th and February 15th, 2020, respectively. Officially, the first case of COVID-19 infection in the Republic of Serbia was registered on March 6th. Herein, we presented...

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Autores principales: Bogdanović, Milenko, Skadrić, Ivan, Atanasijević, Tatjana, Stojković, Oliver, Popović, Vesna, Savić, Slobodan, Mihailović, Zoran, Radnić, Bojana, Aćimović, Tijana, Damjanjuk, Irina, Despotović, Sanja, Barać, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935505/
https://www.ncbi.nlm.nih.gov/pubmed/33681247
http://dx.doi.org/10.3389/fmed.2021.612758
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author Bogdanović, Milenko
Skadrić, Ivan
Atanasijević, Tatjana
Stojković, Oliver
Popović, Vesna
Savić, Slobodan
Mihailović, Zoran
Radnić, Bojana
Aćimović, Tijana
Damjanjuk, Irina
Despotović, Sanja
Barać, Aleksandra
author_facet Bogdanović, Milenko
Skadrić, Ivan
Atanasijević, Tatjana
Stojković, Oliver
Popović, Vesna
Savić, Slobodan
Mihailović, Zoran
Radnić, Bojana
Aćimović, Tijana
Damjanjuk, Irina
Despotović, Sanja
Barać, Aleksandra
author_sort Bogdanović, Milenko
collection PubMed
description In Europe, the first case of coronavirus disease (COVID-19) and the first COVID-19-related death were reported in France on January 24th and February 15th, 2020, respectively. Officially, the first case of COVID-19 infection in the Republic of Serbia was registered on March 6th. Herein, we presented the first case of retrospective detection of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in the post-mortem-obtained vitreous humor (VH), which took place on February 5th, 2020. This is the first death in Europe proven to be caused by COVID-19 by means of post-mortem histopathological and molecular analyses. Based on this finding, it appears that SARS-CoV-2 has been spreading faster and started spreading much earlier than it had been considered and that COVID-19 was probably the cause of the much-reported pneumonia of unknown origin in January and February 2020.
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spelling pubmed-79355052021-03-06 Case Report: Post-mortem Histopathological and Molecular Analyses of the Very First Documented COVID-19-Related Death in Europe Bogdanović, Milenko Skadrić, Ivan Atanasijević, Tatjana Stojković, Oliver Popović, Vesna Savić, Slobodan Mihailović, Zoran Radnić, Bojana Aćimović, Tijana Damjanjuk, Irina Despotović, Sanja Barać, Aleksandra Front Med (Lausanne) Medicine In Europe, the first case of coronavirus disease (COVID-19) and the first COVID-19-related death were reported in France on January 24th and February 15th, 2020, respectively. Officially, the first case of COVID-19 infection in the Republic of Serbia was registered on March 6th. Herein, we presented the first case of retrospective detection of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in the post-mortem-obtained vitreous humor (VH), which took place on February 5th, 2020. This is the first death in Europe proven to be caused by COVID-19 by means of post-mortem histopathological and molecular analyses. Based on this finding, it appears that SARS-CoV-2 has been spreading faster and started spreading much earlier than it had been considered and that COVID-19 was probably the cause of the much-reported pneumonia of unknown origin in January and February 2020. Frontiers Media S.A. 2021-02-19 /pmc/articles/PMC7935505/ /pubmed/33681247 http://dx.doi.org/10.3389/fmed.2021.612758 Text en Copyright © 2021 Bogdanović, Skadrić, Atanasijević, Stojković, Popović, Savić, Mihailović, Radnić, Aćimović, Damjanjuk, Despotović and Barać. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Bogdanović, Milenko
Skadrić, Ivan
Atanasijević, Tatjana
Stojković, Oliver
Popović, Vesna
Savić, Slobodan
Mihailović, Zoran
Radnić, Bojana
Aćimović, Tijana
Damjanjuk, Irina
Despotović, Sanja
Barać, Aleksandra
Case Report: Post-mortem Histopathological and Molecular Analyses of the Very First Documented COVID-19-Related Death in Europe
title Case Report: Post-mortem Histopathological and Molecular Analyses of the Very First Documented COVID-19-Related Death in Europe
title_full Case Report: Post-mortem Histopathological and Molecular Analyses of the Very First Documented COVID-19-Related Death in Europe
title_fullStr Case Report: Post-mortem Histopathological and Molecular Analyses of the Very First Documented COVID-19-Related Death in Europe
title_full_unstemmed Case Report: Post-mortem Histopathological and Molecular Analyses of the Very First Documented COVID-19-Related Death in Europe
title_short Case Report: Post-mortem Histopathological and Molecular Analyses of the Very First Documented COVID-19-Related Death in Europe
title_sort case report: post-mortem histopathological and molecular analyses of the very first documented covid-19-related death in europe
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935505/
https://www.ncbi.nlm.nih.gov/pubmed/33681247
http://dx.doi.org/10.3389/fmed.2021.612758
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