Cargando…

Bile Acid Signaling in Inflammatory Bowel Diseases

Bile acids are a group of chemically different steroids generated at the host/microbial interface. Indeed, while primary bile acids are the end-product of cholesterol breakdown in the host liver, secondary bile acids are the products of microbial metabolism. Primary and secondary bile acids along wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fiorucci, Stefano, Carino, Adriana, Baldoni, Monia, Santucci, Luca, Costanzi, Emanuele, Graziosi, Luigina, Distrutti, Eleonora, Biagioli, Michele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2020
Materias:	Invited Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935738/ https://www.ncbi.nlm.nih.gov/pubmed/33289902 http://dx.doi.org/10.1007/s10620-020-06715-3

Ejemplares similares

Bile Acids Activated Receptors in Inflammatory Bowel Disease
por: Biagioli, Michele, et al.
Publicado: (2021)

Bile Acids Activated Receptors Regulate Innate Immunity
por: Fiorucci, Stefano, et al.
Publicado: (2018)

Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential
por: Carino, Adriana, et al.
Publicado: (2021)

GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation
por: Biagioli, Michele, et al.
Publicado: (2022)

The bile acid receptor GPBAR1 (TGR5) is expressed in human gastric cancers and promotes epithelial-mesenchymal transition in gastric cancer cell lines
por: Carino, Adriana, et al.
Publicado: (2016)

Divergent Effectiveness of Multispecies Probiotic Preparations on Intestinal Microbiota Structure Depends on Metabolic Properties
por: Biagioli, Michele, et al.
Publicado: (2019)

Metabolic Variability of a Multispecies Probiotic Preparation Impacts on the Anti-inflammatory Activity
por: Biagioli, Michele, et al.
Publicado: (2017)

Role of bile acids in inflammatory bowel disease
por: Tiratterra, Elisa, et al.
Publicado: (2018)

The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions
por: Biagioli, Michele, et al.
Publicado: (2019)

Discovery of a Novel Multi-Strains Probiotic Formulation with Improved Efficacy toward Intestinal Inflammation
por: Biagioli, Michele, et al.
Publicado: (2020)

The Bile Acid Sensor FXR Is Required for Immune-Regulatory Activities of TLR-9 in Intestinal Inflammation
por: Renga, Barbara, et al.
Publicado: (2013)

GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated Hepatitis
por: Biagioli, Michele, et al.
Publicado: (2019)

Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics
por: Fiorillo, Bianca, et al.
Publicado: (2021)

Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis
por: Di Giorgio, Cristina, et al.
Publicado: (2022)

Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands
por: Finamore, Claudia, et al.
Publicado: (2016)

Decoding the role of the nuclear receptor SHP in regulating hepatic stellate cells and liver fibrogenesis
por: Cipriani, Sabrina, et al.
Publicado: (2017)

Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation
por: Carino, Adriana, et al.
Publicado: (2019)

Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain
por: Carino, Adriana, et al.
Publicado: (2020)

Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases
por: Festa, Carmen, et al.
Publicado: (2017)

The Bile Acid Sensor FXR Protects against Dyslipidemia and Aortic Plaques Development Induced by the HIV Protease Inhibitor Ritonavir in Mice
por: Mencarelli, Andrea, et al.
Publicado: (2010)

Highly specific blockade of CCR5 inhibits leukocyte trafficking and reduces mucosal inflammation in murine colitis
por: Mencarelli, Andrea, et al.
Publicado: (2016)

Probiotics VSL#3 Protect against Development of Visceral Pain in Murine Model of Irritable Bowel Syndrome
por: Distrutti, Eleonora, et al.
Publicado: (2013)

The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis
por: Cipriani, Sabrina, et al.
Publicado: (2011)

Dissociation of Intestinal and Hepatic Activities of FXR and LXRα Supports Metabolic Effects of Terminal Ileum Interposition in Rodents
por: Mencarelli, Andrea, et al.
Publicado: (2013)

Correction: The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis
por: Cipriani, Sabrina, et al.
Publicado: (2013)

Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction
por: Biagioli, Michele, et al.
Publicado: (2021)

Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice
por: Carino, Adriana, et al.
Publicado: (2017)

Electrolyte and acid-base disorders in inflammatory bowel disease
por: Barkas, Fotis, et al.
Publicado: (2013)

BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis
por: Carino, Adriana, et al.
Publicado: (2017)

Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists
por: Sepe, Valentina, et al.
Publicado: (2016)

Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists
por: De Marino, Simona, et al.
Publicado: (2017)

The HIV matrix protein p17 induces hepatic lipid accumulation via modulation of nuclear receptor transcriptoma
por: Renga, Barbara, et al.
Publicado: (2015)

Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties
por: Finamore, Claudia, et al.
Publicado: (2019)

Bile Acid Signaling in Inflammatory Bowel Disease
por: Bromke, Mariusz A., et al.
Publicado: (2021)

Solomonsterol A, a Marine Pregnane-X-Receptor Agonist, Attenuates Inflammation and Immune Dysfunction in a Mouse Model of Arthritis
por: Mencarelli, Andrea, et al.
Publicado: (2013)

Rheumatological manifestations in inflammatory bowel disease
por: Voulgari, Paraskevi V.
Publicado: (2011)

The history of genetics in inflammatory bowel disease
por: Ek, Weronica E., et al.
Publicado: (2014)

The use of ultrasound in inflammatory bowel disease
por: Kucharzik, Torsten, et al.
Publicado: (2017)

Bile Acids: Key Players in Inflammatory Bowel Diseases?
por: Kriaa, Aicha, et al.
Publicado: (2022)

Endocrine and metabolic manifestations in inflammatory bowel disease
por: Tigas, Stelios, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_6qiet5nftpm01mp296ai62la36