Pharmacological and Genetic Perturbation Establish SIRT5 as a Promising Target in Breast Cancer

SIRT5 is a member of the sirtuin family of NAD(+)-dependent protein lysine deacylases implicated in a variety of physiological processes. SIRT5 removes negatively charged malonyl, succinyl, and glutaryl groups from lysine residues and thereby regulates multiple enzymes involved in cellular metabolis...

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Detalles Bibliográficos
Autores principales: Negrón Abril, Yashira L., Fernandez, Irma R., Hong, Jun Young, Chiang, Ying-Ling, Kutateladze, Dennis A., Zhao, Qingjie, Yang, Min, Hu, Jing, Sadhukhan, Sushabhan, Li, Bo, He, Bin, Remick, Brenna, Bai, Jessica Jingyi, Mullmann, James, Wang, Fangyu, Maymi, Viviana, Dhawan, Ravi, Auwerx, Johan, Southard, Teresa, Cerione, Richard A., Lin, Hening, Weiss, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935767/
https://www.ncbi.nlm.nih.gov/pubmed/33479498
http://dx.doi.org/10.1038/s41388-020-01637-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935767/
https://www.ncbi.nlm.nih.gov/pubmed/33479498
http://dx.doi.org/10.1038/s41388-020-01637-w

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