MCM10 compensates for Myc‐induced DNA replication stress in breast cancer stem‐like cells

Cancer stem‐like cells (CSCs) induce drug resistance and recurrence of tumors when they experience DNA replication stress. However, the mechanisms underlying DNA replication stress in CSCs and its compensation remain unclear. Here, we demonstrate that upregulated c‐Myc expression induces stronger DN...

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Detalles Bibliográficos
Autores principales: Murayama, Takahiko, Takeuchi, Yasuto, Yamawaki, Kaoru, Natsume, Toyoaki, Li, Mengjiao, Marcela, Rojas‐Chaverra N., Nishimura, Tatsunori, Kogure, Yuta, Nakata, Asuka, Tominaga, Kana, Sasahara, Asako, Yano, Masao, Ishikawa, Satoko, Ohta, Tetsuo, Ikeda, Kazuhiro, Horie‐Inoue, Kuniko, Inoue, Satoshi, Seki, Masahide, Suzuki, Yutaka, Sugano, Sumio, Enomoto, Takayuki, Tanabe, Masahiko, Tada, Kei‐ichiro, Kanemaki, Masato T., Okamoto, Koji, Tojo, Arinobu, Gotoh, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935783/
https://www.ncbi.nlm.nih.gov/pubmed/33340428
http://dx.doi.org/10.1111/cas.14776

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