Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation

Herein, a new magnetic metal–organic frameworks based on Fe(3)O(4) (NMMOFs) with porous and high surface area materials were synthesized. Then, NMMOFs were characterized by FT-IR, XRD, SEM, elemental mapping, energy dispersive X-ray (EDS), TG, DTG, VSM, and N(2) adsorption–desorption isotherms (BET)...

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Autores principales: Sepehrmansourie, Hassan, Zarei, Mahmoud, Zolfigol, Mohammad Ali, Babaee, Saeed, Rostamnia, Sadegh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935861/
https://www.ncbi.nlm.nih.gov/pubmed/33674662
http://dx.doi.org/10.1038/s41598-021-84005-2
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author Sepehrmansourie, Hassan
Zarei, Mahmoud
Zolfigol, Mohammad Ali
Babaee, Saeed
Rostamnia, Sadegh
author_facet Sepehrmansourie, Hassan
Zarei, Mahmoud
Zolfigol, Mohammad Ali
Babaee, Saeed
Rostamnia, Sadegh
author_sort Sepehrmansourie, Hassan
collection PubMed
description Herein, a new magnetic metal–organic frameworks based on Fe(3)O(4) (NMMOFs) with porous and high surface area materials were synthesized. Then, NMMOFs were characterized by FT-IR, XRD, SEM, elemental mapping, energy dispersive X-ray (EDS), TG, DTG, VSM, and N(2) adsorption–desorption isotherms (BET). Fe(3)O(4)@Co(BDC)-NH(2) as a magnetic porous catalyst was applied for synthesis of novel fused pyridines and 1,4-dihydropyridines with pyrazole and pyrimidine moieties as suitable drug candidates under ultrasonic irradiation. The significant advantages of the presented methodology are mild, facile workup, high yields, short reaction times, high thermal stability, and reusability of the described NMMOFs catalyst.
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spelling pubmed-79358612021-03-08 Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation Sepehrmansourie, Hassan Zarei, Mahmoud Zolfigol, Mohammad Ali Babaee, Saeed Rostamnia, Sadegh Sci Rep Article Herein, a new magnetic metal–organic frameworks based on Fe(3)O(4) (NMMOFs) with porous and high surface area materials were synthesized. Then, NMMOFs were characterized by FT-IR, XRD, SEM, elemental mapping, energy dispersive X-ray (EDS), TG, DTG, VSM, and N(2) adsorption–desorption isotherms (BET). Fe(3)O(4)@Co(BDC)-NH(2) as a magnetic porous catalyst was applied for synthesis of novel fused pyridines and 1,4-dihydropyridines with pyrazole and pyrimidine moieties as suitable drug candidates under ultrasonic irradiation. The significant advantages of the presented methodology are mild, facile workup, high yields, short reaction times, high thermal stability, and reusability of the described NMMOFs catalyst. Nature Publishing Group UK 2021-03-05 /pmc/articles/PMC7935861/ /pubmed/33674662 http://dx.doi.org/10.1038/s41598-021-84005-2 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Sepehrmansourie, Hassan
Zarei, Mahmoud
Zolfigol, Mohammad Ali
Babaee, Saeed
Rostamnia, Sadegh
Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation
title Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation
title_full Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation
title_fullStr Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation
title_full_unstemmed Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation
title_short Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation
title_sort application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935861/
https://www.ncbi.nlm.nih.gov/pubmed/33674662
http://dx.doi.org/10.1038/s41598-021-84005-2
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