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Single cell transcriptomics reveals lineage trajectory of retinal ganglion cells in wild-type and Atoh7-null retinas

Atoh7 has been believed to be essential for establishing the retinal ganglion cell (RGC) lineage, and Pou4f2 and Isl1 are known to regulate RGC specification and differentiation. Here we report our further study of the roles of these transcription factors. Using bulk RNA-seq, we identify genes regul...

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Detalles Bibliográficos
Autores principales:	Wu, Fuguo, Bard, Jonathan E., Kann, Julien, Yergeau, Donald, Sapkota, Darshan, Ge, Yichen, Hu, Zihua, Wang, Jie, Liu, Tao, Mu, Xiuqian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935890/ https://www.ncbi.nlm.nih.gov/pubmed/33674582 http://dx.doi.org/10.1038/s41467-021-21704-4

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