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Whole-organ analysis of TGF-β-mediated remodelling of the tumour microenvironment by tissue clearing

Tissue clearing is one of the most powerful strategies for a comprehensive analysis of disease progression. Here, we established an integrated pipeline that combines tissue clearing, 3D imaging, and machine learning and applied to a mouse tumour model of experimental lung metastasis using human lung...

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Detalles Bibliográficos
Autores principales: Kubota, Shimpei I., Takahashi, Kei, Mano, Tomoyuki, Matsumoto, Katsuhiko, Katsumata, Takahiro, Shi, Shoi, Tainaka, Kazuki, Ueda, Hiroki R., Ehata, Shogo, Miyazono, Kohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935961/
https://www.ncbi.nlm.nih.gov/pubmed/33674758
http://dx.doi.org/10.1038/s42003-021-01786-y