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A novel methodology for epidemic risk assessment of COVID-19 outbreak

We propose a novel data-driven framework for assessing the a-priori epidemic risk of a geographical area and for identifying high-risk areas within a country. Our risk index is evaluated as a function of three different components: the hazard of the disease, the exposure of the area and the vulnerab...

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Autores principales: Pluchino, A., Biondo, A. E., Giuffrida, N., Inturri, G., Latora, V., Le Moli, R., Rapisarda, A., Russo, G., Zappalà, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935987/
https://www.ncbi.nlm.nih.gov/pubmed/33674627
http://dx.doi.org/10.1038/s41598-021-82310-4
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author Pluchino, A.
Biondo, A. E.
Giuffrida, N.
Inturri, G.
Latora, V.
Le Moli, R.
Rapisarda, A.
Russo, G.
Zappalà, C.
author_facet Pluchino, A.
Biondo, A. E.
Giuffrida, N.
Inturri, G.
Latora, V.
Le Moli, R.
Rapisarda, A.
Russo, G.
Zappalà, C.
author_sort Pluchino, A.
collection PubMed
description We propose a novel data-driven framework for assessing the a-priori epidemic risk of a geographical area and for identifying high-risk areas within a country. Our risk index is evaluated as a function of three different components: the hazard of the disease, the exposure of the area and the vulnerability of its inhabitants. As an application, we discuss the case of COVID-19 outbreak in Italy. We characterize each of the twenty Italian regions by using available historical data on air pollution, human mobility, winter temperature, housing concentration, health care density, population size and age. We find that the epidemic risk is higher in some of the Northern regions with respect to Central and Southern Italy. The corresponding risk index shows correlations with the available official data on the number of infected individuals, patients in intensive care and deceased patients, and can help explaining why regions such as Lombardia, Emilia-Romagna, Piemonte and Veneto have suffered much more than the rest of the country. Although the COVID-19 outbreak started in both North (Lombardia) and Central Italy (Lazio) almost at the same time, when the first cases were officially certified at the beginning of 2020, the disease has spread faster and with heavier consequences in regions with higher epidemic risk. Our framework can be extended and tested on other epidemic data, such as those on seasonal flu, and applied to other countries. We also present a policy model connected with our methodology, which might help policy-makers to take informed decisions.
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spelling pubmed-79359872021-03-08 A novel methodology for epidemic risk assessment of COVID-19 outbreak Pluchino, A. Biondo, A. E. Giuffrida, N. Inturri, G. Latora, V. Le Moli, R. Rapisarda, A. Russo, G. Zappalà, C. Sci Rep Article We propose a novel data-driven framework for assessing the a-priori epidemic risk of a geographical area and for identifying high-risk areas within a country. Our risk index is evaluated as a function of three different components: the hazard of the disease, the exposure of the area and the vulnerability of its inhabitants. As an application, we discuss the case of COVID-19 outbreak in Italy. We characterize each of the twenty Italian regions by using available historical data on air pollution, human mobility, winter temperature, housing concentration, health care density, population size and age. We find that the epidemic risk is higher in some of the Northern regions with respect to Central and Southern Italy. The corresponding risk index shows correlations with the available official data on the number of infected individuals, patients in intensive care and deceased patients, and can help explaining why regions such as Lombardia, Emilia-Romagna, Piemonte and Veneto have suffered much more than the rest of the country. Although the COVID-19 outbreak started in both North (Lombardia) and Central Italy (Lazio) almost at the same time, when the first cases were officially certified at the beginning of 2020, the disease has spread faster and with heavier consequences in regions with higher epidemic risk. Our framework can be extended and tested on other epidemic data, such as those on seasonal flu, and applied to other countries. We also present a policy model connected with our methodology, which might help policy-makers to take informed decisions. Nature Publishing Group UK 2021-03-05 /pmc/articles/PMC7935987/ /pubmed/33674627 http://dx.doi.org/10.1038/s41598-021-82310-4 Text en © The Author(s) 2021, corrected publication 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Pluchino, A.
Biondo, A. E.
Giuffrida, N.
Inturri, G.
Latora, V.
Le Moli, R.
Rapisarda, A.
Russo, G.
Zappalà, C.
A novel methodology for epidemic risk assessment of COVID-19 outbreak
title A novel methodology for epidemic risk assessment of COVID-19 outbreak
title_full A novel methodology for epidemic risk assessment of COVID-19 outbreak
title_fullStr A novel methodology for epidemic risk assessment of COVID-19 outbreak
title_full_unstemmed A novel methodology for epidemic risk assessment of COVID-19 outbreak
title_short A novel methodology for epidemic risk assessment of COVID-19 outbreak
title_sort novel methodology for epidemic risk assessment of covid-19 outbreak
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935987/
https://www.ncbi.nlm.nih.gov/pubmed/33674627
http://dx.doi.org/10.1038/s41598-021-82310-4
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