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Aortic Thrombosis in the Course of Covid-19 Disease; Two Rare Cases

OBJECTIVE: Acute aortic thrombosis and floating aortailiac thrombus are infrequent clinical conditions with high morbidity and mortality rates. It was observed that; SARS-CoV-2 coronavirus disease (Covid-19) caused a hyperinflammation and hyperimmune state and these conditions can result in a hyperc...

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Autores principales: Çora, Ahmet Rıfkı, Çelik, Ersin, Karadem, Kadir Burhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936762/
https://www.ncbi.nlm.nih.gov/pubmed/33689757
http://dx.doi.org/10.1016/j.avsg.2021.02.007
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author Çora, Ahmet Rıfkı
Çelik, Ersin
Karadem, Kadir Burhan
author_facet Çora, Ahmet Rıfkı
Çelik, Ersin
Karadem, Kadir Burhan
author_sort Çora, Ahmet Rıfkı
collection PubMed
description OBJECTIVE: Acute aortic thrombosis and floating aortailiac thrombus are infrequent clinical conditions with high morbidity and mortality rates. It was observed that; SARS-CoV-2 coronavirus disease (Covid-19) caused a hyperinflammation and hyperimmune state and these conditions can result in a hypercoagulation and eventually thrombotic events might occur. METHODS: Here we presented two covid-19 positive patients with rare aortic thrombotic events. RESULTS: Two patients underwent emergent diagnostic tests including computerized tomographic angiography. Total aortic thrombosis just below the renal arising point was evaluated in one patient, and aortic floating thrombus was evaluated in other patient. But despite initial medical therapies, the clinical conditions of the cases worsened and both patients died while on medical therapy before planned surgical intervention applied. CONCLUSIONS: Covid-19 is not only the disease of lungs and inflammatory system also the disease of coagulation and vascular system. Aortic thrombosis is rare and must be kept in mind in Covid-19 patients with peripheral circulation impairment.
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spelling pubmed-79367622021-03-08 Aortic Thrombosis in the Course of Covid-19 Disease; Two Rare Cases Çora, Ahmet Rıfkı Çelik, Ersin Karadem, Kadir Burhan Ann Vasc Surg Article OBJECTIVE: Acute aortic thrombosis and floating aortailiac thrombus are infrequent clinical conditions with high morbidity and mortality rates. It was observed that; SARS-CoV-2 coronavirus disease (Covid-19) caused a hyperinflammation and hyperimmune state and these conditions can result in a hypercoagulation and eventually thrombotic events might occur. METHODS: Here we presented two covid-19 positive patients with rare aortic thrombotic events. RESULTS: Two patients underwent emergent diagnostic tests including computerized tomographic angiography. Total aortic thrombosis just below the renal arising point was evaluated in one patient, and aortic floating thrombus was evaluated in other patient. But despite initial medical therapies, the clinical conditions of the cases worsened and both patients died while on medical therapy before planned surgical intervention applied. CONCLUSIONS: Covid-19 is not only the disease of lungs and inflammatory system also the disease of coagulation and vascular system. Aortic thrombosis is rare and must be kept in mind in Covid-19 patients with peripheral circulation impairment. Elsevier Inc. 2021-05 2021-03-06 /pmc/articles/PMC7936762/ /pubmed/33689757 http://dx.doi.org/10.1016/j.avsg.2021.02.007 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Çora, Ahmet Rıfkı
Çelik, Ersin
Karadem, Kadir Burhan
Aortic Thrombosis in the Course of Covid-19 Disease; Two Rare Cases
title Aortic Thrombosis in the Course of Covid-19 Disease; Two Rare Cases
title_full Aortic Thrombosis in the Course of Covid-19 Disease; Two Rare Cases
title_fullStr Aortic Thrombosis in the Course of Covid-19 Disease; Two Rare Cases
title_full_unstemmed Aortic Thrombosis in the Course of Covid-19 Disease; Two Rare Cases
title_short Aortic Thrombosis in the Course of Covid-19 Disease; Two Rare Cases
title_sort aortic thrombosis in the course of covid-19 disease; two rare cases
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936762/
https://www.ncbi.nlm.nih.gov/pubmed/33689757
http://dx.doi.org/10.1016/j.avsg.2021.02.007
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