T Cell Exhaustion and CAR-T Immunotherapy in Hematological Malignancies

T cell exhaustion has been recognized to play an immunosuppressive role in malignant diseases. Persistent tumor antigen stimulation, the presence of inhibitory immune cells and cytokines in tumor microenvironment (TME), upregulated expression of inhibitory receptors, changes in T cell-related transc...

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Detalles Bibliográficos
Autores principales: Tang, Lu, Zhang, Yinqiang, Hu, Yu, Mei, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936901/
https://www.ncbi.nlm.nih.gov/pubmed/33728333
http://dx.doi.org/10.1155/2021/6616391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936901/
https://www.ncbi.nlm.nih.gov/pubmed/33728333
http://dx.doi.org/10.1155/2021/6616391

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