Hepatic Knockdown of Endothelin Type A Receptor (ETAR) Ameliorates Hepatic Insulin Resistance and Hyperglycemia Through Suppressing p66Shc-Mediated Mitochondrial Fragmentation in High-Fat Diet-Fed Mice

BACKGROUND: Emerging evidence from animal studies and clinical trials indicates that systemic inhibition of endothelin1 (ET1) signaling by endothelin receptor antagonists improves pathological features of diabetes and its complications. It is indicated that endothelin type A receptor (ETAR) plays a...

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Detalles Bibliográficos
Autores principales: Feng, Li, Wang, Songhua, Chen, Feng, Zhang, Cheng, Wang, Qiao, Zhao, Yuting, Zhang, Zifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936928/
https://www.ncbi.nlm.nih.gov/pubmed/33688230
http://dx.doi.org/10.2147/DMSO.S299570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936928/
https://www.ncbi.nlm.nih.gov/pubmed/33688230
http://dx.doi.org/10.2147/DMSO.S299570

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